What is a major risk factor for developing lung cancer?

Smoking tobacco is a major risk factor for developing lung cancer because it is directly linked to the induction of cellular changes in lung tissue that can lead to malignancy. Tobacco smoke contains numerous carcinogens, which are substances that can cause cancer. When inhaled, these carcinogens damage the DNA in lung cells, increasing the risk of mutations that can trigger cancerous growth.

While exposure to secondhand smoke, genetic predisposition, and chronic bronchitis can also contribute to the risk of lung cancer, the overwhelming evidence points to smoking tobacco as the primary and most significant factor. The risk of lung cancer is greatly increased in individuals who smoke compared to nonsmokers. Additionally, smoking is responsible for the majority of lung cancer cases globally, making it a crucial factor in lung cancer risk assessments and prevention strategies.